Type 2 diabetes mellitus is a common metabolism disorder characterized by high glucose in the bloodstream, especially in the case of insulin resistance and relative insulin deficiency. Nowadays, it is very common in middle-aged people and involves such dangerous symptoms as increasing risk of stroke, obesity and heart failure. In Vietnam, besides the common treatment of insulin injection, some herbal medication is used but no unified optimum remedy for the disease yet exists and there is no production of antidiabetic drugs in the domestic market yet. In the development of nanomedicine at the present time, drug design is considered as an innovative tool for researchers to study the mechanisms of diseases at the molecular level. The aim of this article is to review some common protein targets involved in type 2 diabetes, offering a new idea for designing new drug candidates to produce antidiabetic drugs against type 2 diabetes for Vietnamese people.
Posts Tagged ‘Article’
Magnetic storage systems shrink from a million atoms per bit to twelve
Researchers at I.B.M.’s Almaden Research Center have used a scanning tunneling microscope to assemble an array of 96 iron atoms into an antiferromagnetic structure that encodes one byte (eight bits) of information. As reported in the NY Times by John Markoff “ New storage device is very small, at 12 atoms “: SAN JOSE, Calif. — Researchers at I.B.M. have stored and retrieved digital 1s and 0s from an array of just 12 atoms, pushing the boundaries of the magnetic storage of information to the edge of what is possible. The findings, being reported Thursday in the journal Science , could help lead to a new class of nanomaterials for a generation of memory chips and disk drives that will not only have greater capabilities than the current silicon-based computers but will consume significantly less power. And they may offer a new direction for research in quantum computing. … The group at I.B.M.’s Almaden Research Center here, led by Andreas Heinrich, has now created the smallest possible unit of magnetic storage by painstakingly arranging two rows of six iron atoms on a surface of copper nitride. … Although the research took place at a temperature near absolute zero, the scientists wrote that the same experiment could be done at room temperature with as few as 150 atoms. … The remainder of the article quotes Dr. Heinrich as saying that these tiny devices built with scanning tunneling microscopes are primarily of interest as a way to explore the quantum mechanical properties of the antiferromagnetic effect in the hope of developing novel nanomaterials that might lead to quantum computers. He also noted that many research groups are exploring self-assembly methods that could lead to practical manufacturing technologies to replace current microelectronic technologies.
Making computers more error prone could make them much faster and more powerful
Joseph Bates, a longtime Foresight member and computer scientist at Carnegie Mellon and the MIT Media Lab was described in the “Innovator” feature of the January 31-February 6, 2011 issue of Bloomberg Businessweek (unfortunately I could not find this article on the web) as predicting that a computer that ignored some processing tasks necessary to obtain precisely accurate results “would have something like 100,000 times the computing power of a traditional processor.” The advantage of such an approach is that an error of about one percent would produce small or even imperceptible errors for many applications, but would be enormously faster in processing databases, quickly shrinking huge lists of possibilities to small lists that could then be checked by “traditional Intel-style chips” to produce final, precisely accurate results. Bates is quoted as saying that several companies are considering the technology. Bates became interested in A.I. as a boy by reading Isaac Asimov, and believes that the chip he has designed will help computers act more like the human brain by taking shortcuts to “guesstimate” answers. “‘By allowing things to be approximate, you’re a lot closer’ to achieving true artificial intelligence, says Bates.”
Overview of recent direct wafer bonding advances and applications
Direct wafer bonding processes are being increasingly used to achieve innovative stacking structures. Many of them have already been implemented in industrial applications. This article looks at direct bonding mechanisms, processes developed recently and trends. Homogeneous and heterogeneous bonded structures have been successfully achieved with various materials. Active, insulating or conductive materials have been widely investigated. This article gives an overview of Si and SiO 2 direct wafer bonding processes and mechanisms, silicon-on-insulator type bonding, diverse material stacking and the transfer of devices. Direct bonding clearly enables the emergence and development of new applications, such as for microelectronics, microtechnologies, sensors, MEMs, optical devices, biotechnologies and 3D integration.
Smarter Shape Memory Polymers
Shape memory polymers ( SMP s) are a class of smart materials that can switch between two shapes, from a fixed (temporary) shape to a predetermined permanent shape. Shape memory polymers function as actuators, by first forming a heated article into a temporary shape and cooling. Then, by using a second stimulus (i.e. heat), the article can spring back to its original shape. To date, SMP s have been limited to two-way and three-way shape configurations. But now a team at Syracuse University has succeeded in applying the concept of functionally graded materials ( FGM s) to shape memory polymers ( SMP s) and has successfully built a process where sections of one shape memory polymer independently react to different temperature stimuli. Functionally graded materials are defined as synthetic materials where the composition, microstructure and other properties differ along sections of the material. The goal of the research was to apply this theory to SMP s and create a material that could be fixed and recovered in one section of the substance without impacting the response of the other sections. There are numerous applications opportunities for the functionally graded SMP s, from low-cost temperature labels that could measure temperatures in areas that are not accessible by conventional methods or not amenable to continuous monitoring, to indirectly indicate sterilization completions, or for incorporation into product packaging (for shipping industry or food storage) to indicate the maximum temperature for a product exposure. Read More Paper
Shape-controlled synthesis of NIR absorbing branched gold nanoparticles and morphology stabilization with alkanethiols
Gold nanoparticles are ideal candidates for clinical applications if their plasmon absorption band is situated in the near infrared region (NIR) of the electromagnetic spectrum. Various parameters, including the nanoparticle shape, strongly influence the position of this absorption band. The aim of this study is to produce stabilized NIR absorbing branched gold nanoparticles with potential for biomedical applications. Hereto, the synthesis procedure for branched gold nanoparticles is optimized varying the different synthesis parameters. By subsequent electroless gold plating the plasmon absorption band is shifted to 747.2 nm. The intrinsic unstable nature of the nanoparticles’ morphology can be clearly observed by a spectral shift and limits their use in real applications. However, in this article we show how the stabilization of the branched structure can be successfully achieved by exchanging the initial capping agent for different alkanethiols and disulfides. Furthermore, when…
Graphene and its one-dimensional patterns: from basic properties towards applications
Graphene, a carbon material discovered in 2004 by a group of scientists at the University of Manchester, UK, has been attracting significant attention in both fundamental and applied studies. Due to the rapid increase in the number of articles on this material since its discovery, a range of readers, particularly those just beginning to learn about this material, are turning to various different sources. The purpose of this article is to create a bridge between the key aspects of this material in experimental and theoretical investigations, as well as in fundamental and applied studies, aiming to provide a basic understanding of this material for those who are new to it. The presentation in this article is thus not particularly academic. The content focuses on four themes, including fabrication methods, basic properties, potential for application and some typical research directions for this magic carbon material.
The future of nanomedicine looks promising, but only if we learn from the past.: An article from: Health Law Review
Product DescriptionThis digital document is an article from Health Law Review, published by Health Law Institute on December 22, 2004. The length of the article is 1607 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.Citation DetailsTitle: The future of nanomedic… More >>
The future of nanomedicine looks promising, but only if we learn from the past.: An article from: Health Law Review
Nanomedicine: important new concepts for otolaryngology.: An article from: Ear, Nose and Throat Journal
Product DescriptionThis digital document is an article from Ear, Nose and Throat Journal, published by Thomson Gale on September 1, 2007. The length of the article is 1001 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.Citation DetailsTitle: Nanomedicine: import… More >>
Nanomedicine: important new concepts for otolaryngology.: An article from: Ear, Nose and Throat Journal
The future of nanomedicine: the founder of the Nanofactory Collaboration is innovating medicine molecule by molecule.: An article from: The Futurist
Product DescriptionThis digital document is an article from The Futurist, published by World Future Society on January 1, 2010. The length of the article is 1017 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available immediately after purchase. You can view it with any web browser.Citation DetailsTitle: The future of nanomedicine: the founder of the Nanofactory Colla… More >>
The future of nanomedicine: the founder of the Nanofactory Collaboration is innovating medicine molecule by molecule.: An article from: The Futurist



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